6L0B

Crystal structure of dihydroorotase in complex with fluorouracil from Saccharomyces cerevisiae

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, B, D	Dihydroorotase	polymer	372	41478.4	4	UniProt (P20051) Pfam (PF04909) In PDB	Saccharomyces cerevisiae (Baker's yeast)	DHOase
2	A, C, B, D	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
3	A, C, B, D	5-FLUOROURACIL	non-polymer		130.1	4	Chemie (URF)
4		water	water		18.0	226	Chemie (HOH)

Sequence modifications

A, C, B, D: 1 - 364 (UniProt: P20051)

PDB	External Database	Details
Leu 365	-	expression tag
Glu 366	-	expression tag
His 367	-	expression tag
His 368	-	expression tag
His 369	-	expression tag
His 370	-	expression tag
His 371	-	expression tag
His 372	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	165913.4
Non-Polymers*	Number of molecules	12
	Total formula weight	1043.6
All*	Total formula weight	166957.0

*Water molecules are not included.