6L0B
Crystal structure of dihydroorotase in complex with fluorouracil from Saccharomyces cerevisiae
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, C, B, D) | Dihydroorotase | polymer | 372 | 41478.4 | 4 | UniProt (P20051) Pfam (PF04909) | Saccharomyces cerevisiae (Baker's yeast) | DHOase |
| 2 | E, F, H, I, K... (A, C, B, D) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 3 | G, J, M, P (A, C, B, D) | 5-FLUOROURACIL | non-polymer | 130.1 | 4 | Chemie (URF) | |||
| 4 | Q, R, S, T (A, C, B, D) | water | water | 18.0 | 226 | Chemie (HOH) |
Sequence modifications
A, C, B, D: 1 - 364 (UniProt: P20051)
| PDB | External Database | Details |
|---|---|---|
| Leu 365 | - | expression tag |
| Glu 366 | - | expression tag |
| His 367 | - | expression tag |
| His 368 | - | expression tag |
| His 369 | - | expression tag |
| His 370 | - | expression tag |
| His 371 | - | expression tag |
| His 372 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 165913.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1043.6 | |
| All* | Total formula weight | 166957.0 |






