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6KZI

Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine derivatives

Replaces:  4MED
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase pim-1polymer28933292.71UniProt (P11309)
Pfam (PF00069)
Homo sapiens (Human)
2B
(A)
4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-aminenon-polymer344.91Chemie (RTX)
Sequence modifications
A: 29 - 313 (UniProt: P11309)
PDBExternal DatabaseDetails
Gly 25-expression tag
Pro 26-expression tag
His 27-expression tag
Met 28-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33292.7
Non-Polymers*Number of molecules1
Total formula weight344.9
All*Total formula weight33637.6
*Water molecules are not included.

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PDB entries from 2026-02-04

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