6KY6
Crystal structure of a thermostable aldo-keto reductase Tm1743 in complexs with inhibitor epalrestat in space group P3221cc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 2,5-diketo-D-gluconic acid reductase | polymer | 274 | 31402.9 | 2 | UniProt (Q9X265) Pfam (PF00248) | Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) | Oxidoreductase,aldo/keto reductase family |
| 2 | C, G (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | D, H (A, B) | {5-[(2E)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}acetic acid | non-polymer | 319.4 | 2 | Chemie (EPR) | |||
| 4 | E, F, I, J, K (A, B) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 305 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62805.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2302.9 | |
| All* | Total formula weight | 65108.8 |
