6KY0
Crystal structural of active-site human glutathione-specific gamma-glutamylcyclotransferase 2(ChaC2) mutant with Glutamate 74 replaced by Glutamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Glutathione-specific gamma-glutamylcyclotransferase 2 | polymer | 181 | 20447.1 | 3 | UniProt (Q8WUX2) Pfam (PF04752) | Homo sapiens (Human) | Gamma-GCG 2,Cation transport regulator-like protein 2 |
| 2 | D, E, F (A, B, C) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 174 (UniProt: Q8WUX2)
| PDB | External Database | Details |
|---|---|---|
| Lys -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Gln 74 | Glu 74 | engineered mutation |
| Gly 82 | Arg 82 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 61341.4 | |
| All* | Total formula weight | 61341.4 |
