6KXI
Crystal Structure Of NDM-1 Metallo-beta-lactamase In Complex With Inhibitor NO9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-lactamase | polymer | 246 | 26045.3 | 2 | UniProt (E5KIY2) | Escherichia coli | Beta-lactamase NDM-1,BlaNDM-1,BlaNDM-1 metallo beta lactamase,Metallo-beta-lactamase,NDM-1,NDM-1 metallo-beta-lactamase,New Delhi metallo-beta-lactamase NDM-1,Subclass B1 metallo-beta-lactamase,Subclass B1 metallo-beta-lactamase NDM-1 |
| 2 | C, D, E, J, K... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 3 | F, G, H, M (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | I, N (A, B) | 2,5-dimethyl-4-sulfamoyl-furan-3-carboxylic acid | non-polymer | 219.2 | 2 | Chemie (NO9) | |||
| 5 | O, P (A, B) | water | water | 18.0 | 628 | Chemie (HOH) |
Sequence modifications
A, B: 29 - 270 (UniProt: E5KIY2)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Ser 26 | - | expression tag |
| His 27 | - | expression tag |
| Met 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52090.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1215.1 | |
| All* | Total formula weight | 53305.7 |
