6KWQ

Crystal structure of enterovirus 71 polymerase elongation complex (native form)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RNA-dependent RNA polymerase	polymer	468	53360.5	1	UniProt (A0A023RBB6) Pfam (PF00680) UniProt (by SIFTS) (M4QLY4)	Enterovirus A71
2	B (B)	RNA (31-MER)	polymer	31	10038.0	1		synthetic construct
3	C (C)	RNA (5'-R(*UP*GP*UP*UP*CP*CP*GP*AP*GP*AP*GP*A)-3')	polymer	12	3852.3	1		synthetic construct
4	D, E, H, I, J (A, B)	MAGNESIUM ION	non-polymer		24.3	5	Chemie (MG)
5	F (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
6	G (A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
7	K (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
8	L, M, N (A, B, C)	water	water		18.0	648	Chemie (HOH)

Sequence modifications

A: 1 - 462 (UniProt: A0A023RBB6)

PDB	External Database	Details
His 463	-	expression tag
His 464	-	expression tag
His 465	-	expression tag
His 466	-	expression tag
His 467	-	expression tag
His 468	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	67250.9
Non-Polymers*	Number of molecules	8
	Total formula weight	385.1
All*	Total formula weight	67636.0

*Water molecules are not included.