6KTL
Crystal structure of scyllo-inositol dehydrogenase R178A mutant, complexed with NAD and myo-inositol, from Paracoccus laeviglucosivorans
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity | polymer | 380 | 41315.6 | 4 | UniProt (K7ZP76) Pfam (PF01408) Pfam (PF02894) In PDB | Paracoccus laeviglucosivorans | |
2 | A, B, C | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
3 | A, B, C, D | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
4 | D | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE | non-polymer | 180.2 | 1 | Chemie (INS) | |||
5 | water | water | 18.0 | 1171 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 372 (UniProt: K7ZP76)
PDB | External Database | Details |
---|---|---|
Ser 72 | Asn 72 | See sequence details |
Ala 178 | Arg 178 | engineered mutation |
Leu 373 | - | expression tag |
Glu 374 | - | expression tag |
His 375 | - | expression tag |
His 376 | - | expression tag |
His 377 | - | expression tag |
His 378 | - | expression tag |
His 379 | - | expression tag |
His 380 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 165262.4 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 3011.0 | |
All* | Total formula weight | 168273.4 |