6KTK
Crystal structure of scyllo-inositol dehydrogenase R178A mutant, complexed with NADH and L-glucono-1,5-lactone, from Paracoccus laeviglucosivorans
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity | polymer | 380 | 41315.6 | 4 | UniProt (K7ZP76) Pfam (PF01408) Pfam (PF22725) In PDB | Paracoccus laeviglucosivorans | |
2 | A, B, C, D | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 4 | Chemie (NAI) | |||
3 | A, D | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
4 | A, B, C, D | L-glucono-1,5-lactone | non-polymer | 178.1 | 4 | Chemie (8S0) | |||
5 | water | water | 18.0 | 930 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 372 (UniProt: K7ZP76)
PDB | External Database | Details |
---|---|---|
Ser 72 | Asn 72 | See sequence details |
Ala 178 | Arg 178 | engineered mutation |
Leu 373 | - | expression tag |
Glu 374 | - | expression tag |
His 375 | - | expression tag |
His 376 | - | expression tag |
His 377 | - | expression tag |
His 378 | - | expression tag |
His 379 | - | expression tag |
His 380 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 165262.4 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 3762.8 | |
All* | Total formula weight | 169025.2 |