6KSB
Crystal Structure of E447A M130G Acyl-CoA Dehydrogenase FadE5 mutant from Mycobacteria smegmatis in complex with C16CoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Acyl-CoA dehydrogenase | polymer | 611 | 66469.1 | 2 | UniProt (A0A0D6G5A8) Pfam (PF02770) Pfam (PF00441) Pfam (PF12806) UniProt (by SIFTS) (Q3L887) | Mycobacterium smegmatis | |
| 2 | C, G (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 3 | D, H (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 4 | E, I (A, B) | PALMITIC ACID | non-polymer | 256.4 | 2 | Chemie (PLM) | |||
| 5 | F, J (A, B) | COENZYME A | non-polymer | 767.5 | 2 | Chemie (COA) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 666 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 611 (UniProt: A0A0D6G5A8)
| PDB | External Database | Details |
|---|---|---|
| Gly 130 | Met 130 | engineered mutation |
| Ala 447 | Glu 447 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 132938.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3803.2 | |
| All* | Total formula weight | 136741.3 |
