6KS0

Crystal structure of the human adiponectin receptor 1

Replaces:  3WXV

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Adiponectin receptor protein 1	polymer	305	35040.8	1	UniProt (Q96A54) Pfam (PF03006) In PDB	Homo sapiens (Human)	Progestin and adipoQ receptor family member 1,Progestin and adipoQ receptor family member I
2	H	The heavy chain variable domain (Antibody)	polymer	119	13160.6	1		Mus musculus (Mouse)
3	L	The light chain variable domain (Antibody)	polymer	107	11647.9	1		Mus musculus (Mouse)
4	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
5	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
6		water	water		18.0	29	Chemie (HOH)

Sequence modifications

A: 89 - 375 (UniProt: Q96A54)

PDB	External Database	Details
Met -17	-	initiating methionine
Asp -16	-	expression tag
Tyr -15	-	expression tag
Lys -14	-	expression tag
Asp -13	-	expression tag
Asp -12	-	expression tag
Asp -11	-	expression tag
Asp -10	-	expression tag
Lys -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	59849.3
Non-Polymers*	Number of molecules	2
	Total formula weight	160.4
All*	Total formula weight	60009.7

*Water molecules are not included.