6KP2
Quadruple mutant plasmodium falciparum dihydrofolate reductase complexed with B10042
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bifunctional dihydrofolate reductase-thymidylate synthase | polymer | 608 | 71908.1 | 2 | UniProt (D9N170) Pfam (PF00186) Pfam (PF00303) | Plasmodium falciparum (malaria parasite P. falciparum) | |
| 2 | C, G (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | D, H (A, B) | 5-(3-chlorophenyl)-6-(3-phenoxypropyl)pyrimidine-2,4-diamine | non-polymer | 354.8 | 2 | Chemie (DQ3) | |||
| 4 | E, I (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F, J (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 716 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 143816.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2574.6 | |
| All* | Total formula weight | 146390.9 |
