6KO0
The crystal structue of PDE10A complexed with 1i
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | polymer | 322 | 37292.0 | 2 | UniProt (Q9Y233) In PDB | Homo sapiens (Human) | |
| 2 | A, B | 3-[2-(5-methyl-1-phenyl-benzimidazol-2-yl)ethyl]chromen-4-one | non-polymer | 380.4 | 2 | Chemie (DKU) | |||
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 196 | Chemie (HOH) |
Sequence modifications
A, B: 449 - 769 (UniProt: Q9Y233)
| PDB | External Database | Details |
|---|---|---|
| Met 448 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74584.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 940.3 | |
| All* | Total formula weight | 75524.3 |
