6KN8
Structure of human cardiac thin filament in the calcium bound state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Actin, alpha skeletal muscle | polymer | 375 | 41862.6 | 15 | UniProt (P68135) Pfam (PF00022) | Oryctolagus cuniculus (Rabbit) | Alpha-actin-1 |
| 2 | P, Q, W, X (P, Q, W, X) | Tropomyosin alpha-1 chain | polymer | 274 | 31555.1 | 4 | UniProt (P09493) Pfam (PF00261) | Homo sapiens (Human) | Alpha-tropomyosin,Tropomyosin-1 |
| 3 | R, S, Y, Z (R, S, Y, Z) | Tropomyosin alpha-1 chain | polymer | 31 | 3528.1 | 4 | UniProt (P09493) Pfam (PF00261) | Homo sapiens (Human) | Alpha-tropomyosin,Tropomyosin-1 |
| 4 | AA, T (T, a) | Troponin T, cardiac muscle | polymer | 174 | 21446.2 | 2 | UniProt (P45379) Pfam (PF00992) | Homo sapiens (Human) | TnTc,Cardiac muscle troponin T,cTnT |
| 5 | BA, U (U, b) | Troponin I, cardiac muscle | polymer | 126 | 14430.8 | 2 | UniProt (P19429) Pfam (PF00992) | Homo sapiens (Human) | Cardiac troponin I |
| 6 | CA, V (V, c) | Troponin C, slow skeletal and cardiac muscles | polymer | 160 | 18288.3 | 2 | UniProt (P63316) Pfam (PF13833) Pfam (PF13499) | Homo sapiens (Human) | TN-C |
| 7 | DA, EA, FA, GA, HA... (A, B, C, D, E...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 15 | Chemie (ADP) |
Sequence modifications
R, S, Y, Z: 1 - 29 (UniProt: P09493)
| PDB | External Database | Details |
|---|---|---|
| Ala -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 29 |
| Total formula weight | 876602.4 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 6408.0 | |
| All* | Total formula weight | 883010.4 |
