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6KHS

Crystal structure of HEMK2/TRMT112 in complex with SAH and MEQ

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AMethyltransferase N6AMT1polymer21422978.41UniProt (Q9Y5N5)
Pfam (PF05175)
In PDB
Homo sapiens (Human)HemK methyltransferase family member 2,M.HsaHemK2P
2BMultifunctional methyltransferase subunit TRM112-like proteinpolymer12514215.41UniProt (Q9UI30)
Pfam (PF03966)
In PDB
Homo sapiens (Human)
3AN5-METHYLGLUTAMINEnon-polymer160.21Chemie (MEQ)
4AS-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
5waterwater18.0215Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight37193.7
Non-Polymers*Number of molecules2
Total formula weight544.6
All*Total formula weight37738.3
*Water molecules are not included.

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PDB entries from 2024-07-17

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