6KHS
Crystal structure of HEMK2/TRMT112 in complex with SAH and MEQ
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methyltransferase N6AMT1 | polymer | 214 | 22978.4 | 1 | UniProt (Q9Y5N5) Pfam (PF05175) | Homo sapiens (Human) | HemK methyltransferase family member 2,M.HsaHemK2P |
| 2 | B (B) | Multifunctional methyltransferase subunit TRM112-like protein | polymer | 125 | 14215.4 | 1 | UniProt (Q9UI30) Pfam (PF03966) | Homo sapiens (Human) | |
| 3 | C (A) | N5-METHYLGLUTAMINE | non-polymer | 160.2 | 1 | Chemie (MEQ) | |||
| 4 | D (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 215 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37193.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 544.6 | |
| All* | Total formula weight | 37738.3 |
