6KHS
Crystal structure of HEMK2/TRMT112 in complex with SAH and MEQ
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methyltransferase N6AMT1 | polymer | 214 | 22978.4 | 1 | UniProt (Q9Y5N5) Pfam (PF05175) | Homo sapiens (Human) | HemK methyltransferase family member 2,M.HsaHemK2P |
| 2 | B (B) | Multifunctional methyltransferase subunit TRM112-like protein | polymer | 125 | 14215.4 | 1 | UniProt (Q9UI30) Pfam (PF03966) | Homo sapiens (Human) | |
| 3 | C (A) | N5-METHYLGLUTAMINE | non-polymer | 160.2 | 1 | Chemie (MEQ) PubChem (922) PubChem (439925) PubChem (9812846) | |||
| 4 | D (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (13792) PubChem (177678424) PubChem (189149) PubChem (439155) PubChem (25210495) PubChem (21125603) PubChem (44361184) PubChem (25203782) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (57544532) PubChem (52224400) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (5284331) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (71170554) PubChem (13231890) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (164157219) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 215 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37193.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 544.6 | |
| All* | Total formula weight | 37738.3 |
