6KHF
Crystal structure of CLK3 in complex with CX-4945
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dual specificity protein kinase CLK3 | polymer | 490 | 58665.5 | 1 | UniProt (P49761) Pfam (PF00069) In PDB | Homo sapiens (Human) | CDC-like kinase 3 |
| 2 | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | non-polymer | 349.8 | 1 | Chemie (3NG) | |||
| 3 | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A: 1 - 490 (UniProt: P49761)
| PDB | External Database | Details |
|---|---|---|
| Asp 155 | Arg 155 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 58665.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 349.8 | |
| All* | Total formula weight | 59015.3 |
