6KGS
Crystal structure of Penicillin binding protein 3 (PBP3) from Mycobacterium tuerculosis, complexed with meropenem
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Penicillin-binding protein PbpB | polymer | 562 | 59801.0 | 1 | UniProt (L0T911) Pfam (PF03717) Pfam (PF00905) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Penicillin-binding protein 3,PBP3 |
| 2 | B (A) | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid | non-polymer | 385.5 | 1 | Chemie (MER) | |||
| 3 | C, D (A) | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) | |||
| 4 | E (A) | water | water | 18.0 | 139 | Chemie (HOH) |
Sequence modifications
A: 123 - 679 (UniProt: L0T911)
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | expression tag |
| Pro 119 | - | expression tag |
| Leu 120 | - | expression tag |
| Gly 121 | - | expression tag |
| Ser 122 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 59801.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 503.3 | |
| All* | Total formula weight | 60304.4 |
