6KEY

Structural basis for the regulation of inducible nitric oxide synthase (iNOS) by the SPRY domain-containing SOCS box protein 2 (SPSB2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	SPRY domain-containing SOCS box protein 2	polymer	209	22896.6	1	UniProt (Q99619) Pfam (PF00622) In PDB	Homo sapiens (Human)	SSB-2
2	B	Nitric oxide synthase, inducible	polymer	9	1075.2	1	UniProt (P35228) In PDB	Homo sapiens	Hepatocyte NOS,HEP-NOS,Inducible NO synthase,iNOS,NOS type II,Peptidyl-cysteine S-nitrosylase NOS2
3		water	water		18.0	122	Chemie (HOH)

Sequence modifications

A: 22 - 220 (UniProt: Q99619)

PDB	External Database	Details
Met 20	-	expression tag
Gly 21	-	expression tag
Gly 221	-	expression tag
Ser 222	-	expression tag
His 223	-	expression tag
His 224	-	expression tag
His 225	-	expression tag
His 226	-	expression tag
His 227	-	expression tag
His 228	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	23971.8
All*	Total formula weight	23971.8

*Water molecules are not included.