6KBI
Crystal structure of ErbB3 N418Q mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Receptor tyrosine-protein kinase erbB-3 | polymer | 620 | 68303.5 | 2 | UniProt (P21860) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843) | Homo sapiens (Human) | Proto-oncogene-like protein c-ErbB-3,Tyrosine kinase-type cell surface receptor HER3 |
| 2 | C, D (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | E, F, G, H, I... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 13 | Chemie (NAG) |
Sequence modifications
A, B: 1 - 620 (UniProt: P21860)
| PDB | External Database | Details |
|---|---|---|
| Gln 418 | Asn 437 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 136607.0 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2875.7 | |
| All* | Total formula weight | 140331.5 |
