6KBA
X-ray structure of human PPARalpha ligand binding domain-Wy14643 co-crystals obtained by co-crystallization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor alpha | polymer | 273 | 30856.1 | 1 | UniProt (Q07869) Pfam (PF00104) | Homo sapiens (Human) | PPAR-alpha,Nuclear receptor subfamily 1 group C member 1 |
| 2 | B, C (A) | 2-({4-CHLORO-6-[(2,3-DIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL}SULFANYL)ACETIC ACID | non-polymer | 323.8 | 2 | Chemie (WY1) | |||
| 3 | D (A) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A: 200 - 468 (UniProt: Q07869)
| PDB | External Database | Details |
|---|---|---|
| Gly 196 | - | expression tag |
| Ser 197 | - | expression tag |
| His 198 | - | expression tag |
| Met 199 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30856.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 647.6 | |
| All* | Total formula weight | 31503.6 |
