6K72

eIF2(aP) - eIF2B complex

Replaces:  6JLX

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Translation initiation factor eIF-2B subunit alpha	polymer	305	33754.1	2	UniProt (Q14232) Pfam (PF01008) In PDB	Homo sapiens (Human)	eIF-2B GDP-GTP exchange factor subunit alpha
2	C, D	Translation initiation factor eIF-2B subunit beta	polymer	351	39039.5	2	UniProt (P49770) Pfam (PF01008) In PDB	Homo sapiens (Human)	S20I15,S20III15,eIF-2B GDP-GTP exchange factor subunit beta
3	E, F	Translation initiation factor eIF-2B subunit gamma	polymer	452	50304.2	2	UniProt (Q9NR50) Pfam (PF00483) In PDB	Homo sapiens (Human)	eIF2Bg,eIF-2B GDP-GTP exchange factor subunit gamma
4	G, H	Translation initiation factor eIF-2B subunit delta	polymer	523	57640.2	2	UniProt (Q9UI10) Pfam (PF01008) In PDB	Homo sapiens (Human)	eIF-2B GDP-GTP exchange factor subunit delta
5	I, J	Translation initiation factor eIF-2B subunit epsilon	polymer	721	80466.6	2	UniProt (Q13144) Pfam (PF02020) In PDB	Homo sapiens (Human)	eIF-2B GDP-GTP exchange factor subunit epsilon
6	K, L	Eukaryotic translation initiation factor 2 subunit 1	polymer	315	36161.2	2	UniProt (P05198) Pfam (PF00575) Pfam (PF07541) In PDB	Homo sapiens (Human)	Eukaryotic translation initiation factor 2 subunit alpha,eIF-2alpha
7	M	Eukaryotic translation initiation factor 2 subunit 2	polymer	333	38454.5	1	UniProt (P20042) Pfam (PF01873) In PDB	Homo sapiens (Human)	Eukaryotic translation initiation factor 2 subunit beta,eIF-2-beta
8	P	Eukaryotic translation initiation factor 2 subunit 3	polymer	472	51178.4	1	UniProt (P41091) Pfam (PF03144) Pfam (PF09173) Pfam (PF00009) In PDB	Homo sapiens (Human)	Eukaryotic translation initiation factor 2 subunit gamma X,eIF-2gX

Contents of the asymmetric unit

Polymers	Number of chains	14
	Total formula weight	684364.7
All*	Total formula weight	684364.7

*Water molecules are not included.