6K71

eIF2 - eIF2B complex

Replaces:  6JLW

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Translation initiation factor eIF-2B subunit alpha	polymer	305	33754.1	2	UniProt (Q14232) Pfam (PF01008)	Homo sapiens (Human)	eIF-2B GDP-GTP exchange factor subunit alpha
2	C, D (C, D)	Translation initiation factor eIF-2B subunit beta	polymer	351	39039.5	2	UniProt (P49770) Pfam (PF01008)	Homo sapiens (Human)	S20I15,S20III15,eIF-2B GDP-GTP exchange factor subunit beta
3	E, F (E, F)	Translation initiation factor eIF-2B subunit gamma	polymer	452	50304.2	2	UniProt (Q9NR50) Pfam (PF00483) Pfam (PF25084)	Homo sapiens (Human)	eIF2Bg,eIF-2B GDP-GTP exchange factor subunit gamma
4	G, H (G, H)	Translation initiation factor eIF-2B subunit delta	polymer	523	57640.2	2	UniProt (Q9UI10) Pfam (PF01008)	Homo sapiens (Human)	eIF-2B GDP-GTP exchange factor subunit delta
5	I, J (I, J)	Translation initiation factor eIF-2B subunit epsilon	polymer	721	80466.6	2	UniProt (Q13144) Pfam (PF02020)	Homo sapiens (Human)	eIF-2B GDP-GTP exchange factor subunit epsilon
6	K (K)	Eukaryotic translation initiation factor 2 subunit 1	polymer	315	36161.2	1	UniProt (P05198) Pfam (PF00575) Pfam (PF07541)	Homo sapiens (Human)	Eukaryotic translation initiation factor 2 subunit alpha,eIF-2alpha
7	L (M)	Eukaryotic translation initiation factor 2 subunit 2	polymer	333	38454.5	1	UniProt (P20042) Pfam (PF01873)	Homo sapiens (Human)	Eukaryotic translation initiation factor 2 subunit beta,eIF-2-beta
8	M (P)	Eukaryotic translation initiation factor 2 subunit 3	polymer	472	51178.4	1	UniProt (P41091) Pfam (PF00009) Pfam (PF03144) Pfam (PF09173)	Homo sapiens (Human)	Eukaryotic translation initiation factor 2 subunit gamma X,eIF-2gX

Contents of the asymmetric unit

Polymers	Number of chains	13
	Total formula weight	648203.5
All*	Total formula weight	648203.5

*Water molecules are not included.