6K5I

Crystal structure of the E148D/R147A/F317A mutant CLC-ec1 in the presence of 20 mM NaBr

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	H(+)/Cl(-) exchange transporter ClcA	polymer	473	50214.2	2	UniProt (E9TIA0) In PDB	Escherichia coli MS 117-3
2	C, E	Fab fragment, heavy chain	polymer	222	23823.0	2		Mus musculus
3	D, F	Fab fragment, light chain	polymer	211	23088.4	2		Mus musculus
4	A, B	BROMIDE ION	non-polymer		79.9	2	Chemie (BR)

Sequence modifications

A, B: 1 - 473 (UniProt: E9TIA0)

PDB	External Database	Details
Ala 147	Arg 147	engineered mutation
Asp 148	Glu 148	engineered mutation
Ala 317	Phe 317	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	194251.3
Non-Polymers*	Number of molecules	2
	Total formula weight	159.8
All*	Total formula weight	194411.1

*Water molecules are not included.