6K1K
Human nucleosome core particle with H2A.X S139E variant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E (A, E) | Histone H3.1 | polymer | 139 | 15719.4 | 2 | UniProt (P68431) Pfam (PF00125) | Homo sapiens (Human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
2 | B, F (B, F) | Histone H4 | polymer | 106 | 11676.7 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (Human) | |
3 | C, G (C, G) | Histone H2AX | polymer | 146 | 15496.9 | 2 | UniProt (P16104) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (Human) | H2a/x,Histone H2A.X |
4 | D, H (D, H) | Histone H2B type 1-J | polymer | 129 | 14217.5 | 2 | UniProt (P06899) Pfam (PF00125) | Homo sapiens (Human) | Histone H2B.1,Histone H2B.r,H2B/r |
5 | I (I) | DNA (145-MER) | polymer | 145 | 44761.5 | 1 | Homo sapiens | ||
6 | J (J) | DNA (145-MER) | polymer | 145 | 44752.5 | 1 | Homo sapiens | ||
7 | K, L (C, G) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
8 | AA, BA, CA, EA, FA... (I, J, H) | MANGANESE (II) ION | non-polymer | 54.9 | 33 | Chemie (MN) | |||
9 | DA, UA (I, J) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
10 | AB, BB, CB, DB, EB... (F, G, H, I, J...) | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A, E: 0 - 135 (UniProt: P68431)
B, F: 0 - 102 (UniProt: P62805)
C, G: 0 - 142 (UniProt: P16104)
D, H: -3 - 122 (UniProt: P06899)
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
Glu 139 | Ser 140 | variant |
PDB | External Database | Details |
---|---|---|
Gly -6 | - | expression tag |
Ser -5 | - | expression tag |
His -4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 203735.2 | |
Non-Polymers* | Number of molecules | 37 |
Total formula weight | 1962.1 | |
All* | Total formula weight | 205697.2 |