6K1J

Human nucleosome core particle with H2A.X variant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	Histone H3.1	polymer	139	15719.4	2	UniProt (P68431) Pfam (PF00125)	Homo sapiens (Human)	Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
2	B, F (B, F)	Histone H4	polymer	106	11676.7	2	UniProt (P62805) Pfam (PF15511)	Homo sapiens (Human)
3	C, G (C, G)	Histone H2AX	polymer	146	15454.9	2	UniProt (P16104) Pfam (PF00125) Pfam (PF16211)	Homo sapiens (Human)	H2a/x,Histone H2A.X
4	D, H (D, H)	Histone H2B type 1-J	polymer	129	14217.5	2	UniProt (P06899) Pfam (PF00125)	Homo sapiens (Human)	Histone H2B.1,Histone H2B.r,H2B/r
5	I (I)	DNA (145-MER)	polymer	145	44749.7	1		Homo sapiens
6	J (J)	DNA (145-MER)	polymer	145	44740.6	1		Homo sapiens
7	K, M (C, H)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
8	L, N, O, P, Q... (D, I, J)	MANGANESE (II) ION	non-polymer		54.9	12	Chemie (MN)
9	AA, BA, CA, DA, EA... (C, D, E, F, G...)	water	water		18.0	30	Chemie (HOH)

Sequence modifications

A, E: 0 - 135 (UniProt: P68431)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

B, F: 0 - 102 (UniProt: P62805)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

C, G: 0 - 142 (UniProt: P16104)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

D, H: -3 - 122 (UniProt: P06899)

PDB	External Database	Details
Gly -6	-	expression tag
Ser -5	-	expression tag
His -4	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	203627.4
Non-Polymers*	Number of molecules	14
	Total formula weight	730.2
All*	Total formula weight	204357.6

*Water molecules are not included.