6K08
Crystal structure of REV7(R124A/A135D) in complex with a Shieldin3 fragment
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Mitotic spindle assembly checkpoint protein MAD2B | polymer | 219 | 25239.2 | 1 | UniProt (Q9UI95) Pfam (PF02301) In PDB | Homo sapiens (Human) | Mitotic arrest deficient 2-like protein 2,MAD2-like protein 2,REV7 homolog,hREV7 |
2 | B | Shieldin complex subunit 3 | polymer | 30 | 3358.9 | 1 | UniProt (Q6ZNX1) In PDB | Homo sapiens (Human) | REV7-interacting novel NHEJ regulator 1,Shield complex subunit 3 |
3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
4 | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A: 7 - 211 (UniProt: Q9UI95)
B: 46 - 74 (UniProt: Q6ZNX1)
PDB | External Database | Details |
---|---|---|
Met -7 | - | expression tag |
Gly -6 | - | expression tag |
Ser -5 | - | expression tag |
Ser -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
His 1 | - | expression tag |
His 2 | - | expression tag |
Ser 3 | - | expression tag |
Gln 4 | - | expression tag |
Asp 5 | - | expression tag |
Pro 6 | - | expression tag |
Ala 124 | Arg 124 | engineered mutation |
Asp 135 | Ala 135 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Met 45 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 28598.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 96.1 | |
All* | Total formula weight | 28694.2 |