6K06
Crystal structure of Importin-alpha and phosphomimetic GM130
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peptide from Golgin subfamily A member 2 | polymer | 53 | 5797.6 | 1 | UniProt (Q08379) | Homo sapiens (Human) | phosphomimetic GM130,130 kDa cis-Golgi matrix protein,GM130,GM130 autoantigen,Golgin-95 |
| 2 | B (C) | Importin subunit alpha-1 | polymer | 433 | 46898.7 | 1 | UniProt (P52293) Pfam (PF01749) Pfam (PF00514) Pfam (PF16186) | Mus musculus (Mouse) | Importin alpha P1,Karyopherin subunit alpha-2,Pendulin,Pore targeting complex 58 kDa subunit,PTAC58,RAG cohort protein 1,SRP1-alpha |
| 3 | C, D (A, C) | water | water | 18.0 | 442 | Chemie (HOH) |
Sequence modifications
A: 1 - 48 (UniProt: Q08379)
C: 70 - 498 (UniProt: P52293)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asp 25 | Ser 37 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 66 | - | expression tag |
| Ser 67 | - | expression tag |
| His 68 | - | expression tag |
| Met 69 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52696.3 | |
| All* | Total formula weight | 52696.3 |
