6JXR

Structure of human T cell receptor-CD3 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	a, b	T-cell surface glycoprotein CD3 zeta chain	polymer	164	18723.4	2	UniProt (P20963) Pfam (PF11628) Pfam (PF02189) In PDB	Homo sapiens (Human)	T-cell receptor T3 zeta chain
2	d	T-cell surface glycoprotein CD3 delta chain	polymer	171	18949.5	1	UniProt (P04234) Pfam (PF16680) Pfam (PF02189) In PDB	Homo sapiens (Human)	T-cell receptor T3 delta chain
3	f, e	T-cell surface glycoprotein CD3 epsilon chain	polymer	207	23174.2	2	UniProt (P07766) Pfam (PF16681) Pfam (PF02189) In PDB	Homo sapiens (Human)	T-cell surface antigen T3/Leu-4 epsilon chain
4	g	T-cell surface glycoprotein CD3 gamma chain	polymer	182	20493.5	1	UniProt (P09693) Pfam (PF16680) Pfam (PF02189) In PDB	Homo sapiens (Human)	T-cell receptor T3 gamma chain
5	m	T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha constant	polymer	252	28308.7	1	UniProt (A0A0B4J271) UniProt (A0N4Z6) UniProt (P01848) Pfam (PF07686) Pfam (PF09291) In PDB	Homo sapiens (Human)
6	n	T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2	polymer	291	32498.5	1	UniProt (A0A0G2JMB4) UniProt (A0A0K0K1A5) UniProt (P0DSE2) Pfam (PF07686) Pfam (PF07654) In PDB	Homo sapiens (Human)	TR beta chain TRBV1901J2S701C*02

Sequence modifications

m: 22 - 114 (UniProt: A0A0B4J271)

PDB	External Database	Details
Lys 115	-	linker

m: 116 - 132 (UniProt: A0N4Z6)

PDB	External Database	Details
Asp 133	-	linker

m: 134 - 273 (UniProt: P01848)
n: 22 - 112 (UniProt: A0A0K0K1A5)

n: 121 - 134 (UniProt: P0DSE2)
n: 135 - 312 (UniProt: A0A0G2JMB4)

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.