6JVO

Crystal structure of human MTH1 in complex with compound MI1022

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	7,8-dihydro-8-oxoguanine triphosphatase	polymer	155	17840.3	2	UniProt (P36639) Pfam (PF00293) In PDB	Homo sapiens (Human)	2-hydroxy-dATP diphosphatase,8-oxo-dGTPase,Nucleoside diphosphate-linked moiety X motif 1,Nudix motif 1
2	A, B	N4-cyclopropyl-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine	non-polymer		248.3	2	Chemie (CJ6)
3		water	water		18.0	246	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	35680.5
Non-Polymers*	Number of molecules	2
	Total formula weight	496.7
All*	Total formula weight	36177.2

*Water molecules are not included.