6JVK
Crystal structure of human MTH1 in complex with compound MI1012
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 7,8-dihydro-8-oxoguanine triphosphatase | polymer | 156 | 17971.5 | 2 | UniProt (P36639) Pfam (PF00293) | Homo sapiens (Human) | 2-hydroxy-dATP diphosphatase,8-oxo-dGTPase,Nucleoside diphosphate-linked moiety X motif 1,Nudix motif 1 |
| 2 | C (A) | N4-methyl-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine | non-polymer | 222.3 | 1 | Chemie (CEU) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 260 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35942.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 222.3 | |
| All* | Total formula weight | 36165.2 |
