6JVI

Crystal structure of human MTH1 in complex with compound MI0861

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	7,8-dihydro-8-oxoguanine triphosphatase	polymer	156	17971.5	2	UniProt (P36639) Pfam (PF00293)	Homo sapiens (Human)	2-hydroxy-dATP diphosphatase,8-oxo-dGTPase,Nucleoside diphosphate-linked moiety X motif 1,Nudix motif 1
2	C, E (A, B)	(4R)-4-(2-methoxyphenyl)-4,6,7,8-tetrahydroquinoline-2,5(1H,3H)-dione	non-polymer		271.3	2	Chemie (95R)
3	D, F (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	G, H (A, B)	water	water		18.0	145	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	35942.9
Non-Polymers*	Number of molecules	4
	Total formula weight	734.7
All*	Total formula weight	36677.7

*Water molecules are not included.