6JVH
Crystal structure of human MTH1 in complex with compound MI0320
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 7,8-dihydro-8-oxoguanine triphosphatase | polymer | 156 | 17971.5 | 2 | UniProt (P36639) Pfam (PF00293) | Homo sapiens (Human) | 2-hydroxy-dATP diphosphatase,8-oxo-dGTPase,Nucleoside diphosphate-linked moiety X motif 1,Nudix motif 1 |
| 2 | C, D (A, B) | 4-amino-6-fluoroquinoline-3-carbohydrazide | non-polymer | 220.2 | 2 | Chemie (95L) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35942.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 440.4 | |
| All* | Total formula weight | 36383.3 |
