6JUH
structure of CavAb in complex with efonidipine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Ion transport protein | polymer | 267 | 31090.8 | 4 | UniProt (A8EVM5) Pfam (PF00520) Pfam (PF08016) | Arcobacter butzleri RM4018 | |
| 2 | E, I, L, R (A, B, C, D) | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 677.9 | 4 | Chemie (MC3) | |||
| 3 | F, J, M, N (A, B, C) | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 678.9 | 4 | Chemie (PX4) | |||
| 4 | G, O, P, S (A, C, D) | SN-GLYCEROL-3-PHOSPHATE | non-polymer | 172.1 | 4 | Chemie (G3P) | |||
| 5 | H, K (B, C) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | Q (D) | 2-[phenyl-(phenylmethyl)amino]ethyl (4~{R})-5-(5,5-dimethyl-2-oxidanylidene-1,3,2$l^{5}-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate | non-polymer | 631.7 | 1 | Chemie (C9X) |
Sequence modifications
A, B, C, D: 1001 - 1267 (UniProt: A8EVM5)
| PDB | External Database | Details |
|---|---|---|
| Asp 1177 | Glu 177 | engineered mutation |
| Asp 1178 | Ser 178 | engineered mutation |
| Asn 1181 | Met 181 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 124363.3 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 6827.6 | |
| All* | Total formula weight | 131190.9 |
