6JR0

Crystal structure of the human nucleosome phased with 12 selenium atoms

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	Histone H3.1	polymer	139	15860.1	2	UniProt (P68431) Pfam (PF00125)	Homo sapiens (Human)	Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
2	B, F (B, F)	Histone H4	polymer	106	11676.7	2	UniProt (P62805) Pfam (PF15511)	Homo sapiens (Human)
3	C, G (C, G)	Histone H2A type 1-B/E	polymer	133	14559.7	2	UniProt (P04908) Pfam (PF00125) Pfam (PF16211)	Homo sapiens (Human)	Histone H2A.2,Histone H2A/a,Histone H2A/m
4	D, H (D, H)	Histone H2B type 1-J	polymer	129	14423.1	2	UniProt (P06899) Pfam (PF00125)	Homo sapiens (Human)	Histone H2B.1,Histone H2B.r,H2B/r
5	I, J (I, J)	DNA (146-MER)	polymer	146	45053.9	2		Homo sapiens
6	K, L, N, O (A, D, E, G)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
7	M, P, Q, R, S... (E, I, J)	MANGANESE (II) ION	non-polymer		54.9	8	Chemie (MN)
8	AA, BA, CA, DA, EA... (E, F, G, H, I...)	water	water		18.0	443	Chemie (HOH)

Sequence modifications

A, E: 0 - 135 (UniProt: P68431)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

B, F: 0 - 102 (UniProt: P62805)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

C, G: 0 - 129 (UniProt: P04908)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Mse 65	Leu 66	engineered mutation

D, H: 0 - 125 (UniProt: P06899)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Mse 106	Leu 107	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	203147.0
Non-Polymers*	Number of molecules	12
	Total formula weight	581.3
All*	Total formula weight	203728.3

*Water molecules are not included.