6JP6
The X-ray structure of yeast tRNA methyltransferase complex of Trm7 and Trm734 essential for 2'-O-methylation at the first position of anticodon in specific tRNAs
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | tRNA (guanosine(34)-2'-O)-methyltransferase non-catalytic subunit TRM734 | polymer | 1028 | 116391.8 | 2 | UniProt (Q08924) Pfam (PF00400) | Saccharomyces cerevisiae S288c (Baker's yeast) | |
| 2 | B, D (B, D) | tRNA (cytidine(34)/guanosine(34)-2'-O)-methyltransferase | polymer | 325 | 36546.5 | 2 | UniProt (P38238) Pfam (PF01728) | Saccharomyces cerevisiae S288c (Baker's yeast) | 2'-O-ribose RNA methyltransferase TRM7,tRNA methylase 7 |
| 3 | E, F, H, I (A, C) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | G, J (A, C) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 5 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 257 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 1013 (UniProt: Q08924)
B, D: 1 - 310 (UniProt: P38238)
| PDB | External Database | Details |
|---|---|---|
| Leu 1014 | - | expression tag |
| Glu 1015 | - | expression tag |
| Val 1016 | - | expression tag |
| Leu 1017 | - | expression tag |
| Phe 1018 | - | expression tag |
| Gln 1019 | - | expression tag |
| Gly 1020 | - | expression tag |
| Pro 1021 | - | expression tag |
| Ser 1022 | - | expression tag |
| His 1023 | - | expression tag |
| His 1024 | - | expression tag |
| His 1025 | - | expression tag |
| His 1026 | - | expression tag |
| His 1027 | - | expression tag |
| His 1028 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 311 | - | expression tag |
| Glu 312 | - | expression tag |
| Val 313 | - | expression tag |
| Leu 314 | - | expression tag |
| Phe 315 | - | expression tag |
| Gln 316 | - | expression tag |
| Gly 317 | - | expression tag |
| Pro 318 | - | expression tag |
| Ser 319 | - | expression tag |
| His 320 | - | expression tag |
| His 321 | - | expression tag |
| His 322 | - | expression tag |
| His 323 | - | expression tag |
| His 324 | - | expression tag |
| His 325 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 305876.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 860.9 | |
| All* | Total formula weight | 306737.5 |
