6JOU

Crystal structure of the human nucleosome containing H2A.Z.1 S42R

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	Histone H3.1	polymer	139	15719.4	2	UniProt (P68431) Pfam (PF00125)	Homo sapiens (Human)	Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
2	B, F (B, F)	Histone H4	polymer	106	11676.7	2	UniProt (P62805) Pfam (PF15511)	Homo sapiens (Human)
3	C, G (C, G)	Histone H2A.Z	polymer	131	13934.2	2	UniProt (P0C0S5) Pfam (PF00125) Pfam (PF16211)	Homo sapiens (Human)	H2A/z
4	D, H (D, H)	Histone H2B type 1-J	polymer	129	14217.5	2	UniProt (P06899) Pfam (PF00125)	Homo sapiens (Human)	Histone H2B.1,Histone H2B.r,H2B/r
5	I, J (I, J)	DNA (146-MER)	polymer	146	45053.9	2		Homo sapiens
6	K, L, M, N, O... (E, I, J)	MANGANESE (II) ION	non-polymer		54.9	9	Chemie (MN)
7	AA, BA, CA, T, U... (H, I, J, A, B...)	water	water		18.0	195	Chemie (HOH)

Sequence modifications

A, E: 0 - 135 (UniProt: P68431)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

B, F: 0 - 102 (UniProt: P62805)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

C, G: 0 - 127 (UniProt: P0C0S5)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Arg 42	Ser 43	engineered mutation

D, H: 0 - 125 (UniProt: P06899)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	201203.4
Non-Polymers*	Number of molecules	9
	Total formula weight	494.4
All*	Total formula weight	201697.9

*Water molecules are not included.