6JOF

Crystal structure of TrmD from Mycobacterium tuberculosis in complex with active-site inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	tRNA (guanine-N(1)-)-methyltransferase	polymer	238	26170.5	1	UniProt (P9WFY7) Pfam (PF01746) In PDB	Mycobacterium tuberculosis H37Rv
2	A	~{N}-[[4-[(4-azanylpiperidin-1-yl)methyl]phenyl]methyl]-4-oxidanylidene-3~{H}-thieno[2,3-d]pyrimidine-5-carboxamide	non-polymer		397.5	1	Chemie (BWR)
3		water	water		18.0	81	Chemie (HOH)

Sequence modifications

A: 1 - 230 (UniProt: P9WFY7)

PDB	External Database	Details
Gly 231	-	expression tag
Ser 232	-	expression tag
His 233	-	expression tag
His 234	-	expression tag
His 235	-	expression tag
His 236	-	expression tag
His 237	-	expression tag
His 238	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	26170.5
Non-Polymers*	Number of molecules	1
	Total formula weight	397.5
All*	Total formula weight	26568.0

*Water molecules are not included.