6JOF
Crystal structure of TrmD from Mycobacterium tuberculosis in complex with active-site inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | tRNA (guanine-N(1)-)-methyltransferase | polymer | 238 | 26170.5 | 1 | UniProt (P9WFY7) Pfam (PF01746) | Mycobacterium tuberculosis H37Rv | |
| 2 | B (A) | ~{N}-[[4-[(4-azanylpiperidin-1-yl)methyl]phenyl]methyl]-4-oxidanylidene-3~{H}-thieno[2,3-d]pyrimidine-5-carboxamide | non-polymer | 397.5 | 1 | Chemie (BWR) | |||
| 3 | C (A) | water | water | 18.0 | 81 | Chemie (HOH) |
Sequence modifications
A: 1 - 230 (UniProt: P9WFY7)
| PDB | External Database | Details |
|---|---|---|
| Gly 231 | - | expression tag |
| Ser 232 | - | expression tag |
| His 233 | - | expression tag |
| His 234 | - | expression tag |
| His 235 | - | expression tag |
| His 236 | - | expression tag |
| His 237 | - | expression tag |
| His 238 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26170.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 397.5 | |
| All* | Total formula weight | 26568.0 |
