6JME
Crystal structure of human DHODH in complex with inhibitor 0946
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 366 | 39725.3 | 1 | UniProt (Q02127) Pfam (PF01180) | Homo sapiens (Human) | DHOdehase,Dihydroorotate oxidase |
| 2 | B (A) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 3 | C (A) | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 4 | D, E, K (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | F, G, H (A) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 6 | I (A) | LAURYL DIMETHYLAMINE-N-OXIDE | non-polymer | 229.4 | 1 | Chemie (LDA) | |||
| 7 | J (A) | 3-[3,5-bis(fluoranyl)-4-(2-fluorophenyl)phenyl]benzo[f]benzotriazole-4,9-dione | non-polymer | 405.3 | 1 | Chemie (BVU) | |||
| 8 | L, M, N (A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 9 | O (A) | water | water | 18.0 | 278 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39725.3 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1781.5 | |
| All* | Total formula weight | 41506.8 |
