6JL8

Crystal structure of GMP reductase C318A from Trypanosoma brucei

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	GMP reductase	polymer	504	53806.2	2	UniProt (Q57ZS7) Pfam (PF00478) Pfam (PF00571) In PDB	Trypanosoma brucei brucei (strain ILTat1.4)	Guanosine-5'-monophosphate reductase
2		water	water		18.0	19	Chemie (HOH)

Sequence modifications

A, B: 1 - 491 (UniProt: Q57ZS7)

PDB	External Database	Details
Ala 318	Cys 318	engineered mutation
Lys 492	-	expression tag
Leu 493	-	expression tag
Ala 494	-	expression tag
Ala 495	-	expression tag
Ala 496	-	expression tag
Leu 497	-	expression tag
Glu 498	-	expression tag
His 499	-	expression tag
His 500	-	expression tag
His 501	-	expression tag
His 502	-	expression tag
His 503	-	expression tag
His 504	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	107612.4
All*	Total formula weight	107612.4

*Water molecules are not included.