6JJP
Crystal structure of Fab of a PD-1 monoclonal antibody MW11-h317 in complex with PD-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Heavy chain of MW11-h317 | polymer | 220 | 23004.7 | 2 | Homo sapiens | ||
| 2 | B, E (B, E) | light chain of MW11-h317 | polymer | 214 | 23647.4 | 2 | Homo sapiens | ||
| 3 | C, F (C, F) | Programmed cell death protein 1 | polymer | 147 | 16458.3 | 2 | UniProt (Q15116) Pfam (PF07686) | Homo sapiens (Human) | hPD-1 |
| 4 | G, H (G, H) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 2 | In PDB GlyTouCan (G42466VF) | |||
| 5 | I, J, K, L (C, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 6 | M, N, O (A, D, E) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 126220.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1789.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 128895.2 |
