6JJM

Crystal structure of Mumps virus hemagglutinin-neuraminidase bound to the oligosaccharide portion of the GM2 ganglioside

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	HN protein	polymer	489	54268.0	2	UniProt (Q9WAF5) Pfam (PF00423)	Mumps rubulavirus	Hemagglutinin-neuraminidase
2	C, D, F, G (C, D, F, G)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
3	E, H (E, H)	N-acetyl-alpha-neuraminic acid-(2-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose	branched		836.7	2	In PDB GlyTouCan (G28331VY)
4	I, J, L, M (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
5	K, N (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
6	O, P (A, B)	water	water		18.0	467	Chemie (HOH)

Sequence modifications

A, B: 106 - 582 (UniProt: Q9WAF5)

PDB	External Database	Details
Glu 103	-	expression tag
Thr 104	-	expression tag
Gly 105	-	expression tag
Gly 583	-	expression tag
Thr 584	-	expression tag
Lys 585	-	expression tag
His 586	-	expression tag
His 587	-	expression tag
His 588	-	expression tag
His 589	-	expression tag
His 590	-	expression tag
His 591	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	108535.9
Branched	Number of molecules	6
	Total formula weight	3371.1
Non-Polymers*	Number of molecules	6
	Total formula weight	1077.0
All*	Total formula weight	112984.0

*Water molecules are not included.