6JGM
Crystal structure of CDK2 IN complex with Inhibitor NU-6140
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cyclin-dependent kinase 2 | polymer | 299 | 34063.6 | 1 | UniProt (P24941) Pfam (PF00069) | Homo sapiens (Human) | Cell division protein kinase 2 |
| 2 | B (A) | 4-{[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino}-N,N-diethylbenzamide | non-polymer | 422.5 | 1 | Chemie (AQG) | |||
| 3 | C (A) | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34063.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 422.5 | |
| All* | Total formula weight | 34486.1 |
