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6JFU

Crystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
CRISPR-associated endonuclease Cas9polymer1083124913.11Neisseria meningitidis
2B
(B)
sgRNApolymer13543059.41synthetic construct
3C
(C)
target-strand DNApolymer3510845.01synthetic construct
4D
(D)
non-target strandpolymer113358.21synthetic construct
5E, F
(B, C)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight182175.7
Non-Polymers*Number of molecules2
Total formula weight124.1
All*Total formula weight182299.8
*Water molecules are not included.

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PDB entries from 2025-12-24

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