6JCU
Crystal structure of an actin monomer in complex with a nucleator Cordon-Bleu WH2-motif peptide mutant. T22V, H11R
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Actin, alpha skeletal muscle | polymer | 377 | 42110.0 | 2 | UniProt (P68135) Pfam (PF00022) | Oryctolagus cuniculus (Rabbit) | Alpha-actin-1 |
| 2 | B, D (B, D) | Peptide from Protein cordon-bleu | polymer | 22 | 2431.9 | 2 | UniProt (Q5NBX1) Pfam (PF02205) | Mus musculus (Mouse) | |
| 3 | E, H (A, C) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 4 | F, G, I (A, C) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 5 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 281 | Chemie (HOH) |
Sequence modifications
B, D: 66 - 87 (UniProt: Q5NBX1)
| PDB | External Database | Details |
|---|---|---|
| Arg 76 | His 1194 | engineered mutation |
| Val 87 | Thr 1205 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 89083.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1134.6 | |
| All* | Total formula weight | 90218.3 |
