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6JCF

Cryogenic structure of HIV-1 Integrase catalytic core domain by synchrotron

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Integrasepolymer16317838.31UniProt (F2WR52)
Pfam (PF00665)
UniProt (by SIFTS) (P12497)
Human immunodeficiency virus 1
2B, C
(A)
CACODYLATE IONnon-polymer137.02Chemie (CAC)
3D
(A)
waterwater18.029Chemie (HOH)
Sequence modifications
A: 51 - 212 (UniProt: F2WR52)
PDBExternal DatabaseDetails
Gly 50-expression tag
Lys 185Phe 185engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight17838.3
Non-Polymers*Number of molecules2
Total formula weight274.0
All*Total formula weight18112.3
*Water molecules are not included.

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PDB entries from 2025-07-16

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