6JBU
High resolution crystal structure of human FLRT3 LRR domain in complex with mouse CIRL3 Olfactomedin like domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Adhesion G protein-coupled receptor L3 | polymer | 276 | 31650.9 | 1 | UniProt (Q80TS3) Pfam (PF02191) | Mus musculus (Mouse) | CIRL3, Latrophilin-3,Lectomedin-3 |
| 2 | B (B) | Leucine-rich repeat transmembrane protein FLRT3 | polymer | 347 | 39613.0 | 1 | UniProt (Q9NZU0) Pfam (PF13855) | Homo sapiens (Human) | Fibronectin-like domain-containing leucine-rich transmembrane protein 3 |
| 3 | C, D (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | E, F, K (A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 5 | G, H, I, J (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 6 | L, M (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 7 | N, O (A, B) | water | water | 18.0 | 372 | Chemie (HOH) |
Sequence modifications
A: 203 - 461 (UniProt: Q80TS3)
B: 29 - 358 (UniProt: Q9NZU0)
| PDB | External Database | Details |
|---|---|---|
| Ala 196 | - | expression tag |
| Pro 197 | - | expression tag |
| Gly 198 | - | expression tag |
| Asp 199 | - | expression tag |
| Pro 200 | - | expression tag |
| Arg 201 | - | expression tag |
| Glu 202 | - | expression tag |
| Ala 462 | - | expression tag |
| Ala 463 | - | expression tag |
| Ala 464 | - | expression tag |
| His 465 | - | expression tag |
| His 466 | - | expression tag |
| His 467 | - | expression tag |
| His 468 | - | expression tag |
| His 469 | - | expression tag |
| His 470 | - | expression tag |
| His 471 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 22 | - | expression tag |
| Pro 23 | - | expression tag |
| Gly 24 | - | expression tag |
| Asp 25 | - | expression tag |
| Pro 26 | - | expression tag |
| Arg 27 | - | expression tag |
| Glu 28 | - | expression tag |
| Ala 359 | - | expression tag |
| Ala 360 | - | expression tag |
| Ala 361 | - | expression tag |
| His 362 | - | expression tag |
| His 363 | - | expression tag |
| His 364 | - | expression tag |
| His 365 | - | expression tag |
| His 366 | - | expression tag |
| His 367 | - | expression tag |
| His 368 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71263.9 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 949.6 | |
| All* | Total formula weight | 72213.5 |
