6JBU

High resolution crystal structure of human FLRT3 LRR domain in complex with mouse CIRL3 Olfactomedin like domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Adhesion G protein-coupled receptor L3	polymer	276	31650.9	1	UniProt (Q80TS3) Pfam (PF02191) In PDB	Mus musculus (Mouse)	CIRL3, Latrophilin-3,Lectomedin-3
2	B	Leucine-rich repeat transmembrane protein FLRT3	polymer	347	39613.0	1	UniProt (Q9NZU0) Pfam (PF13855) In PDB	Homo sapiens (Human)	Fibronectin-like domain-containing leucine-rich transmembrane protein 3
3	A	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	A	SODIUM ION	non-polymer		23.0	3	Chemie (NA)
5	A	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
6	B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
7		water	water		18.0	372	Chemie (HOH)

Sequence modifications

A: 203 - 461 (UniProt: Q80TS3)

PDB	External Database	Details
Ala 196	-	expression tag
Pro 197	-	expression tag
Gly 198	-	expression tag
Asp 199	-	expression tag
Pro 200	-	expression tag
Arg 201	-	expression tag
Glu 202	-	expression tag
Ala 462	-	expression tag
Ala 463	-	expression tag
Ala 464	-	expression tag
His 465	-	expression tag
His 466	-	expression tag
His 467	-	expression tag
His 468	-	expression tag
His 469	-	expression tag
His 470	-	expression tag
His 471	-	expression tag

B: 29 - 358 (UniProt: Q9NZU0)

PDB	External Database	Details
Ala 22	-	expression tag
Pro 23	-	expression tag
Gly 24	-	expression tag
Asp 25	-	expression tag
Pro 26	-	expression tag
Arg 27	-	expression tag
Glu 28	-	expression tag
Ala 359	-	expression tag
Ala 360	-	expression tag
Ala 361	-	expression tag
His 362	-	expression tag
His 363	-	expression tag
His 364	-	expression tag
His 365	-	expression tag
His 366	-	expression tag
His 367	-	expression tag
His 368	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71263.9
Non-Polymers*	Number of molecules	11
	Total formula weight	949.6
All*	Total formula weight	72213.5

*Water molecules are not included.