6J9U

Complex structure of Lactobacillus casei lactate dehydrogenase penta mutant with pyruvate

Replaces:  3VPF

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	L-lactate dehydrogenase	polymer	326	35670.6	6	UniProt (S6C1Z0) Pfam (PF00056) Pfam (PF02866) UniProt (by SIFTS) (P00343)	Lactobacillus casei subsp. casei ATCC 393	L-LDH
2	G, K, M (A, C, D)	PYRUVIC ACID	non-polymer		88.1	3	Chemie (PYR)
3	H, I, J, L, N... (A, B, C, D, E...)	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
4	S, T, U, V, W... (A, B, C, D, E...)	water	water		18.0	65	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 326 (UniProt: S6C1Z0)

PDB	External Database	Details
Glu 55	Ser 55	engineered mutation
Asp 56	Asn 56	engineered mutation
Lys 164	Glu 164	engineered mutation
Asn 223	Asp 223	engineered mutation
Lys 224	Ala 224	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	214023.9
Non-Polymers*	Number of molecules	12
	Total formula weight	1128.8
All*	Total formula weight	215152.6

*Water molecules are not included.