6J7T

Crystal structure of toxin TglT (unusual type guanylyltransferase-like toxin, Rv1045) mutant D82A from Mycobacterium tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	guanylyltransferase-like toxin	polymer	313	34438.4	1	UniProt (P96356) Pfam (PF08843)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
2	B, C, D, E, F... (A)	MAGNESIUM ION	non-polymer		24.3	15	Chemie (MG)
3	Q (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	R (A)	water	water		18.0	175	Chemie (HOH)

Sequence modifications

A: 2 - 293 (UniProt: P96356)

PDB	External Database	Details
Mse -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Mse 1	-	expression tag
Ala 82	Asp 82	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34438.4
Non-Polymers*	Number of molecules	16
	Total formula weight	456.7
All*	Total formula weight	34895.1

*Water molecules are not included.