6J5J
Cryo-EM structure of the mammalian E-state ATP synthase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | ATP synthase subunit alpha, mitochondrial | polymer | 509 | 55171.1 | 3 | UniProt (P80021) Pfam (PF02874) Pfam (PF00006) Pfam (PF00306) | Sus scrofa (Pig) | ATP synthase F1 subunit alpha,ATP synthase subunit alpha heart isoform,mitochondrial,ATP synthase subunit alpha liver isoform |
| 2 | D, E, F (D, E, F) | ATP synthase subunit beta | polymer | 469 | 50606.7 | 3 | UniProt (K7GLT8) Pfam (PF02874) Pfam (PF00006) Pfam (PF22919) | Sus scrofa (Pig) | |
| 3 | G (J) | ATPase inhibitor, mitochondrial | polymer | 83 | 9500.5 | 1 | UniProt (Q29307) Pfam (PF04568) | Sus scrofa (Pig) | ATP synthase F1 subunit epsilon,Inhibitor of F(1)F(o)-ATPase,IF1 |
| 4 | H (G) | ATP synthase subunit gamma | polymer | 272 | 30121.7 | 1 | UniProt (A0A287A9I8) | Sus scrofa (Pig) | |
| 5 | I (H) | ATP synthase subunit delta, mitochondrial | polymer | 132 | 13852.5 | 1 | UniProt (A0A286ZYL7) Pfam (PF02823) Pfam (PF21335) | Sus scrofa (Pig) | |
| 6 | J (I) | ATP synthase F1 subunit epsilon | polymer | 48 | 5371.3 | 1 | UniProt (A5GFX4) Pfam (PF04627) | Sus scrofa (Pig) | ATP synthase,epsilon subunit |
| 7 | K (S) | ATP synthase subunit O, mitochondrial | polymer | 187 | 20561.3 | 1 | UniProt (Q2EN81) Pfam (PF00213) | Sus scrofa (Pig) | ATP synthase peripheral stalk subunit OSCP |
| 8 | L (b) | ATP synthase peripheral stalk-membrane subunit b | polymer | 209 | 24002.9 | 1 | UniProt (A0A286ZYM6) Pfam (PF05405) UniProt (by SIFTS) (A0A8D0MI69) | Sus scrofa (Pig) | |
| 9 | M (c) | ATP synthase-coupling factor 6, mitochondrial | polymer | 70 | 8245.3 | 1 | UniProt (P13618) Pfam (PF05511) | Sus scrofa (Pig) | ATPase subunit F6,ATP synthase peripheral stalk subunit F6 |
| 10 | N (d) | ATP synthase subunit d, mitochondrial | polymer | 147 | 16904.5 | 1 | UniProt (A0A287B4I0) Pfam (PF05873) | Sus scrofa (Pig) | |
| 11 | O (e) | ATP synthase subunit e | polymer | 63 | 5379.6 | 1 | Sus scrofa | ||
| 12 | P (f) | ATP synthase subunit f, mitochondrial | polymer | 87 | 10198.0 | 1 | UniProt (Q95339) Pfam (PF10206) | Sus scrofa (Pig) | ATP synthase membrane subunit f |
| 13 | Q (g) | ATP synthase subunit g | polymer | 84 | 7166.8 | 1 | Sus scrofa (Pig) | ||
| 14 | R (i) | ATP synthase membrane subunit DAPIT | polymer | 42 | 4861.8 | 1 | UniProt (F1RFD4) Pfam (PF14960) UniProt (by SIFTS) (A0A4X1TQQ5) | Sus scrofa (Pig) | |
| 15 | S (k) | subunit k analog | polymer | 29 | 2486.1 | 1 | Sus scrofa | ||
| 16 | T (8) | ATP synthase protein 8 | polymer | 67 | 7954.4 | 1 | UniProt (Q35914) Pfam (PF00895) | Sus scrofa (Pig) | A6L,F-ATPase subunit 8 |
| 17 | U (a) | ATP synthase subunit a | polymer | 226 | 25054.1 | 1 | UniProt (Q35915) Pfam (PF00119) | Sus scrofa (Pig) | F-ATPase protein 6 |
| 18 | AA, BA, CA, V, W... (K, L, M, N, O...) | Mitochondrial H+ transporting ATP synthase subunit c isoform 1 | polymer | 72 | 7311.6 | 8 | UniProt (Q4VT52) Pfam (PF00137) | Sus scrofa (Pig) | |
| 19 | DA (u) | ATP synthase membrane subunit 6.8PL | polymer | 42 | 3592.4 | 1 | Sus scrofa (Pig) | ||
| 20 | EA, GA, IA (A, B, C) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 3 | Chemie (ATP) | |||
| 21 | FA, HA, JA, LA, NA (A, B, C, D, F) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 22 | KA, MA (D, F) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 30 |
| Total formula weight | 571079.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2497.5 | |
| All* | Total formula weight | 573576.8 |
