6J1L
Crystal Structure Analysis of the ROR gamma(C455E)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Nuclear receptor ROR-gamma | polymer | 267 | 31128.9 | 3 | UniProt (P51449) Pfam (PF00104) In PDB | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
2 | A, B, C | 2-[4-(ethylsulfonyl)phenyl]-N-[2'-fluoro-4'-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)[1,1'-biphenyl]-4-yl]acetamide | non-polymer | 563.5 | 3 | Chemie (B6L) | |||
3 | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A, B, C: 262 - 507 (UniProt: P51449)
PDB | External Database | Details |
---|---|---|
Glu 241 | - | expression tag |
Gly 242 | - | expression tag |
Asp 243 | - | expression tag |
Ile 244 | - | expression tag |
His 245 | - | expression tag |
Met 246 | - | expression tag |
Lys 247 | - | expression tag |
Lys 248 | - | expression tag |
Gly 249 | - | expression tag |
Tyr 250 | - | expression tag |
His 251 | - | expression tag |
His 252 | - | expression tag |
His 253 | - | expression tag |
His 254 | - | expression tag |
His 255 | - | expression tag |
Leu 256 | - | expression tag |
Val 257 | - | expression tag |
Pro 258 | - | expression tag |
Arg 259 | - | expression tag |
Gly 260 | - | expression tag |
Ser 261 | - | expression tag |
Glu 455 | Cys 455 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 93386.8 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1690.5 | |
All* | Total formula weight | 95077.2 |