6IYV
Crystal sturucture of L,D-transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with ertapenem adduct
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | L,D-transpeptidase 2 | polymer | 272 | 29552.7 | 2 | UniProt (I6Y9J2) Pfam (PF17964) Pfam (PF03734) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | LDT 2,Ldt(Mt2) |
| 2 | C, L (B, A) | (2S,3R,4S)-4-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-2-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid | non-polymer | 477.5 | 2 | Chemie (2RG) | |||
| 3 | D, E, F, G, H... (B, A) | GLYCEROL | non-polymer | 92.1 | 10 | Chemie (GOL) | |||
| 4 | I, J (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 5 | K (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | R (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 7 | S, T (B, A) | water | water | 18.0 | 688 | Chemie (HOH) |
Sequence modifications
B, A: 140 - 408 (UniProt: I6Y9J2)
| PDB | External Database | Details |
|---|---|---|
| Ser 137 | - | expression tag |
| Asn 138 | - | expression tag |
| Ala 139 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59105.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2306.4 | |
| All* | Total formula weight | 61411.8 |
